Reviewed By
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.8
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
L-Glutamine (Free-Form)
1 g (1,000 mg)
**
Top Medical Research Studies
9.5
We investigated how a trace element solution combined with L-alanyl-L-glutamine (LG) affects rheumatoid arthritis (RA).
This solution, called LG-WLYS, showed impressive qualities, such as inhibiting harmful cell migration and inflammation.
Our results indicated a shift in macrophage types from M1 to M2, leading to a reduction in various inflammatory markers and improved antioxidant activity.
Overall, LG-WLYS demonstrated strong potential as a therapeutic option for RA, showing both preventive and treatment benefits.
This solution, called LG-WLYS, showed impressive qualities, such as inhibiting harmful cell migration and inflammation.
Our results indicated a shift in macrophage types from M1 to M2, leading to a reduction in various inflammatory markers and improved antioxidant activity.
Overall, LG-WLYS demonstrated strong potential as a therapeutic option for RA, showing both preventive and treatment benefits.
Read More
7
We explored the connection between the LPS/TLR4 pathway and IgA nephropathy (IgAN) in a study using mice models. By establishing various groups, including control and treatment groups with glutamine enteric-coated capsules, our goal was to determine how this pathway could influence immune responses.
The findings revealed that targeting the TLR4 pathway could help regulate immune functions and, potentially, alleviate symptoms of IgAN. This gives hope for new treatment strategies for those affected by this condition.
The findings revealed that targeting the TLR4 pathway could help regulate immune functions and, potentially, alleviate symptoms of IgAN. This gives hope for new treatment strategies for those affected by this condition.
Read More
7
We investigated the role of L-glutamine in T cell differentiation, particularly in oral lichen planus, an autoimmune condition. By studying the ASCT2 transporter's influence on glutamine uptake, we discovered that higher levels of glutamine were associated with increased T cell activity.
However, when we interfered with this uptake, it led to higher reactive oxygen species levels, which reduced T cell differentiation. Our findings suggest that while glutamine uptake can influence T cells, targeting this pathway might offer new treatment avenues for autoimmune diseases, though more research is needed.
However, when we interfered with this uptake, it led to higher reactive oxygen species levels, which reduced T cell differentiation. Our findings suggest that while glutamine uptake can influence T cells, targeting this pathway might offer new treatment avenues for autoimmune diseases, though more research is needed.
Read More
Most Useful Reviews
7.5
Improves mood
45 people found this helpful
Hello! I have leaky intestines and food intolerance. I decided to try this product instead of the pricier Thron brand. After two months, I've noticed improved gut health, with normalised stool and reduced food intolerance symptoms, including skin reactions. Additionally, my mood and energy levels have significantly increased, making my training sessions better. I previously took various dietary supplements without much benefit until I realised my intestines needed care. I plan to continue using this product regularly, as the effects are evident.
Read More
9
Healing leaky gut
1 people found this helpful
I take this supplement to address Leaky Gut syndrome due to my autoimmune disorder. Used alongside beef gelatin, it has been working well for me.
Read More
8
Restores digestion
1 people found this helpful
This product is beneficial for restoring the intestines, especially for those with digestive issues and autoimmune diseases. I acquired it based on my doctor's recommendation.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.8
- All Researches
9.5
We investigated how a trace element solution combined with L-alanyl-L-glutamine (LG) affects rheumatoid arthritis (RA).
This solution, called LG-WLYS, showed impressive qualities, such as inhibiting harmful cell migration and inflammation.
Our results indicated a shift in macrophage types from M1 to M2, leading to a reduction in various inflammatory markers and improved antioxidant activity.
Overall, LG-WLYS demonstrated strong potential as a therapeutic option for RA, showing both preventive and treatment benefits.
This solution, called LG-WLYS, showed impressive qualities, such as inhibiting harmful cell migration and inflammation.
Our results indicated a shift in macrophage types from M1 to M2, leading to a reduction in various inflammatory markers and improved antioxidant activity.
Overall, LG-WLYS demonstrated strong potential as a therapeutic option for RA, showing both preventive and treatment benefits.
Read More
7
We explored the connection between the LPS/TLR4 pathway and IgA nephropathy (IgAN) in a study using mice models. By establishing various groups, including control and treatment groups with glutamine enteric-coated capsules, our goal was to determine how this pathway could influence immune responses.
The findings revealed that targeting the TLR4 pathway could help regulate immune functions and, potentially, alleviate symptoms of IgAN. This gives hope for new treatment strategies for those affected by this condition.
The findings revealed that targeting the TLR4 pathway could help regulate immune functions and, potentially, alleviate symptoms of IgAN. This gives hope for new treatment strategies for those affected by this condition.
Read More
7
We investigated the role of L-glutamine in T cell differentiation, particularly in oral lichen planus, an autoimmune condition. By studying the ASCT2 transporter's influence on glutamine uptake, we discovered that higher levels of glutamine were associated with increased T cell activity.
However, when we interfered with this uptake, it led to higher reactive oxygen species levels, which reduced T cell differentiation. Our findings suggest that while glutamine uptake can influence T cells, targeting this pathway might offer new treatment avenues for autoimmune diseases, though more research is needed.
However, when we interfered with this uptake, it led to higher reactive oxygen species levels, which reduced T cell differentiation. Our findings suggest that while glutamine uptake can influence T cells, targeting this pathway might offer new treatment avenues for autoimmune diseases, though more research is needed.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Improves mood
45 people found this helpful
Hello! I have leaky intestines and food intolerance. I decided to try this product instead of the pricier Thron brand. After two months, I've noticed improved gut health, with normalised stool and reduced food intolerance symptoms, including skin reactions. Additionally, my mood and energy levels have significantly increased, making my training sessions better. I previously took various dietary supplements without much benefit until I realised my intestines needed care. I plan to continue using this product regularly, as the effects are evident.
Read More
9
Healing leaky gut
1 people found this helpful
I take this supplement to address Leaky Gut syndrome due to my autoimmune disorder. Used alongside beef gelatin, it has been working well for me.
Read More
8
Restores digestion
1 people found this helpful
This product is beneficial for restoring the intestines, especially for those with digestive issues and autoimmune diseases. I acquired it based on my doctor's recommendation.
Read More
9
Significant antibody reduction
I am taking this to heal a leaky gut that contributes to my autoimmune disorder thyroid antibodies. The benefit has been a significant decrease in my antibodies. I also follow a gluten-free diet alongside this and some other supplements, including NAC, selenium, and Vitamin D.
Read More
7.5
Helpful for treatment
4 people found this helpful
I only take supplements on my doctor's advice. My gastroenterologist recommended this during the pandemic, and when I fell ill with COVID-19, I started taking it. Although I'm not an expert, I felt it helped significantly with my treatment. I recommend it for both viral infections and for combating inflammatory processes.
Read More
Frequently Asked Questions
7.5
Improves mood
45 people found this helpful
Hello! I have leaky intestines and food intolerance. I decided to try this product instead of the pricier Thron brand. After two months, I've noticed improved gut health, with normalised stool and reduced food intolerance symptoms, including skin reactions. Additionally, my mood and energy levels have significantly increased, making my training sessions better. I previously took various dietary supplements without much benefit until I realised my intestines needed care. I plan to continue using this product regularly, as the effects are evident.
9
Significant antibody reduction
I am taking this to heal a leaky gut that contributes to my autoimmune disorder thyroid antibodies. The benefit has been a significant decrease in my antibodies. I also follow a gluten-free diet alongside this and some other supplements, including NAC, selenium, and Vitamin D.
7.5
Increased energy
1 people found this helpful
Recently, I’ve struggled with lower immunity, energy, and stamina, feeling more fatigued. After a month of consistent use of this popular product, I've felt lighter and less tired upon waking. I plan to continue taking it.
2
No effect noted
4 people found this helpful
The UC Huanyu Review articles concerning the effect on UC Crohn do not seem to help me in remission. During the active phase, I noticed no effect at all.
9
Healing leaky gut
1 people found this helpful
I take this supplement to address Leaky Gut syndrome due to my autoimmune disorder. Used alongside beef gelatin, it has been working well for me.
7.5
Helpful for treatment
4 people found this helpful
I only take supplements on my doctor's advice. My gastroenterologist recommended this during the pandemic, and when I fell ill with COVID-19, I started taking it. Although I'm not an expert, I felt it helped significantly with my treatment. I recommend it for both viral infections and for combating inflammatory processes.
9
Essential amino acid
3 people found this helpful
An excellent amino acid, glutamine is vital for healing leaky gut. As a conditionally essential amino acid, the body can produce it, but additional sources are crucial in cases of weakened immunity or nervous disorders.
8
Restores digestion
1 people found this helpful
This product is beneficial for restoring the intestines, especially for those with digestive issues and autoimmune diseases. I acquired it based on my doctor's recommendation.
9.5
We investigated how a trace element solution combined with L-alanyl-L-glutamine (LG) affects rheumatoid arthritis (RA).
This solution, called LG-WLYS, showed impressive qualities, such as inhibiting harmful cell migration and inflammation.
Our results indicated a shift in macrophage types from M1 to M2, leading to a reduction in various inflammatory markers and improved antioxidant activity.
Overall, LG-WLYS demonstrated strong potential as a therapeutic option for RA, showing both preventive and treatment benefits.
This solution, called LG-WLYS, showed impressive qualities, such as inhibiting harmful cell migration and inflammation.
Our results indicated a shift in macrophage types from M1 to M2, leading to a reduction in various inflammatory markers and improved antioxidant activity.
Overall, LG-WLYS demonstrated strong potential as a therapeutic option for RA, showing both preventive and treatment benefits.
7
We investigated the role of L-glutamine in T cell differentiation, particularly in oral lichen planus, an autoimmune condition. By studying the ASCT2 transporter's influence on glutamine uptake, we discovered that higher levels of glutamine were associated with increased T cell activity.
However, when we interfered with this uptake, it led to higher reactive oxygen species levels, which reduced T cell differentiation. Our findings suggest that while glutamine uptake can influence T cells, targeting this pathway might offer new treatment avenues for autoimmune diseases, though more research is needed.
However, when we interfered with this uptake, it led to higher reactive oxygen species levels, which reduced T cell differentiation. Our findings suggest that while glutamine uptake can influence T cells, targeting this pathway might offer new treatment avenues for autoimmune diseases, though more research is needed.
References
- Wang S, Yin J, Liu Y, Jin M, Wang Q, et al. An organic state trace element solution for rheumatoid arthritis treatment by modulating macrophage phenotypic from M1 to M2. Biomed Pharmacother. 2024;170:116025. 10.1016/j.biopha.2023.116025
- He H, Shen M, Tang Y, Sun W, Xu X. LPS/TLR4 Pathway Regulates IgA1 Secretion to Induce IgA Nephropathy. Altern Ther Health Med. 2024;30:419.
- Li W, Ling Z, Wang J, Su Z, Lu J, et al. ASCT2-mediated glutamine uptake promotes Th1 differentiation via ROS-EGR1-PAC1 pathway in oral lichen planus. Biochem Pharmacol. 2023;216:115767. 10.1016/j.bcp.2023.115767
